Evaluation of Rhodiola rosea Root Fraction as a Functional Cosmetic Ingredient

To develop functional cosmetic material using <i>Rhodiola rosea</i>, the biological activities such as anti-oxidant, anti-inflammatory, astringent, anti-tyrosinase, and anti-elastase activity were investigated with methanol, <i>n</i>-hexane, chloroform, ethyl acetate, n-butanol, water fractions of <i>R. rosea</i> Root. DPPH ABTS radical scavenging acetate fraction increased in a dosedependent manner; higher than other fractions. The total phenolic content also showed relatively high value 500.485±4.848 mgGAE/g. significantly decreased LPS-induced NO production IL-6 secretion compared untreated control cells at above 5-100 μg/mL concentrations. astringent was 94.31% concentration 500 μg/mL, similar to that tannic acid. mushroom tyrosinase inhibition abilities hexane, butanol 10.44%, 17.53%, 14.55%, respectively, 100 μg/mL. Furthermore, an elastase rate effect 45.46% 45.07% fraction. These results indicate R. rosea Root would be used natural beauty-food industries.